PRODUCT DESCRIPTION:
Recombinant Mouse IL-20 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 152 amino acids and having a total molecular mass of 17,584 Dalton. The rmIL-20 is purified by proprietary chromatographic techniques.

SOURCE:
Escherichia Coli.

FORMULATION:
Lyophilized from a concentrated (1mg/ml) solution containing no additives.

PURITY:
Greater than 95.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE
(c) Anion-exchange FPLC.

STORAGE:
Although stable at room temperature for 3 weeks, it should be stored desiccated below -18°C. Upon reconstitution store at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

SOLUBILITY:

BIOLOGICAL ACTIVITY:
rmIL-20 is fully biologically active when compared to standard. The biological activity was determined by measuring the dose dependent activation of STAT3 in human epidermal keratinocytes (HEK2a cells). Significant STAT3 activation is observed with >100 ng/mL of recombinant mouse IL-20.