PRODUCT DESCRIPTION:
Adiponectin / Acrp30 (247amino acids) is adipocyte complement-related protein of 30 kDa and exclusively expressed in differentiated adipocytes. APM-1 (Acrp30) is a member of the complement factor C1q family and consists of signal sequence, Non-homologous sequence, collagen domain and domain (gAcrp30). Adiponectin (Acrp30) expression is reduced in a variety of obese and insulin-resistant states in human, monkeys and mice. Injection of Acrp30(247aa) or gAcrp30 (globular domain) lowers serum glucose and free fatty acid level in mice.

SOURCE:
Escherichia Coli.

FORMULATION:
1mg/ml solution containing 20mM Tris-HCl pH7.5, 50mM NaCl, 5mM DTT and 10% Glycerol.

PURITY:
Greater than 95.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.

STORAGE:
Liquid APM-1 although stable at 14C° for 1 week, should be stored below -18°C. Please prevent freeze-thaw cycles.